Masked hypertension (MHT), defined as nonelevated blood pressure (BP) in the clinic setting and elevated BP assessed by ambulatory monitoring, is associated with increased risk of target organ damage, cardiovascular disease, and mortality. Currently, no estimate of MHT prevalence exists for the general US population. After pooling data from the Masked Hypertension Study (n = 811), a cross-sectional clinical investigation of systematic differences between clinic BP and ambulatory BP (ABP) in a community sample of employed adults in the New York City metropolitan area (2005–2012), and the National Health and Nutrition Examination Survey (NHANES;
2005–2010; n = 9,316), an ongoing nationally representative US survey, we used multiple imputation to impute ABP-defined hypertension status for NHANES participants and estimate MHT prevalence among the 139 million US adults with nonelevated clinic BP, no history of overt cardiovascular disease, and no use of antihypertensive medication. The estimated US prevalence of MHT in 2005–2010 was 12.3% of the adult population (95% confidence interval: 10.0, 14.5)—approximately 17.1 million persons aged ?21 years.
Consistent with prior research, estimated MHT prevalence was higher among older persons, males, and those with prehypertension or diabetes. To our knowledge, this study provides the first estimate of US MHT prevalence—nearly 1 in 8 adults with nonelevated clinic BP—and suggests that millions of US adults may be misclassified as not having hypertension.
Source: https://academic.oup.com/aje/article-abstract/185/3/194/2915788/Prevalence-of-Masked-Hypertension-Among-US-Adults
Saturday, May 16, 2026
Dimenhydrinate (Dramamine) - Nausea - Patient guide - Quick tips
Travel-related nausea can produce major disruption when patients need reliable function for business trips, caregiving, or long commutes. Dimenhydrinate remains common option, but value depends on correct timing and risk-aware use. Patients often improve most when they combine preventive dosing with hydration, sleep preparation, and trigger management rather than relying on repeated rescue doses. For pre-visit planning, patients can review dimenhydrinate treatment details and record common episode patterns. Cost and convenience discussions should include refill access, sedation burden, and impact on work tasks. Low medication price may still carry high indirect cost if excessive drowsiness reduces productivity or driving safety. Patients should report sedation intensity, dry mouth, concentration changes, and any near-miss safety events. Clinicians can then adjust strategy to preserve symptom control while reducing functional impairment. Symptom journals improve follow-up quality. Useful fields include departure time, route type, food timing, caffeine intake, sleep duration, motion intensity, and dose timing relative to travel. Pattern review can reveal avoidable triggers such as heavy meals before departure or prolonged screen focus in moving vehicles. Targeted routine changes may reduce symptom frequency without increasing medication burden. Supportive measures remain central. Smaller pre-travel meals, steady fluid intake, forward visual focus, fresh-air breaks, and minimizing rapid head turns can reduce nausea intensity. Patients should avoid alcohol and caution other sedating drugs while using dimenhydrinate. Persistent nausea despite prevention should trigger reassessment for alternative diagnoses such as migraine-associated nausea, vestibular disorders, medication side effects, or gastrointestinal disease. Red flags requiring urgent review include repeated vomiting with poor fluid retention, severe abdominal pain, blood in vomit, confusion, or fainting. For broader prevention and follow-up tools, patients can use nausea support resources and bring written logs to appointments. Reliable dimenhydrinate outcomes usually come from preventive planning, careful monitoring, and timely escalation when warning signs appear. Consistency helps.
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